多肽名称 | Ac-APP₇₇₀ (96-110) (cyclized) |
纯度 | HPLC ≥ 95% |
描述 | This cyclized peptide which is homologous to the heparin-binding domain of APP, binds strongly to heparin and inhibits binding of ¹²⁵I-labeled APP to heparin (IC₅₀= 10⁻⁷M). The peptide blocks the heparan sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth. |
存储 | -20°C |
参考论文 | D.H.Small et al., J. Neurosci., 14, 2117 (1994) |
分子量 | 1918.24 |
多肽序列(单字母) | Ac-NWCKRGRKQCKTHPH-NH₂ (Disulfide bond) |
多肽序列(三字母) | Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH₂ (Disulfide bond) |
Ac-APP₇₇₀ (96-110) (cyclized)
Elisa Q.
2020-11-04T19:08:15+08:00