| 多肽名称 | Alpha-synuclein (46-58) Heavy |
| 纯度 | HPLC ≥ 95% |
| 描述 | Alpha-synuclein (46-58) Heavy is derived from the alpha-synuclein intrinsically disordered protein which is found in the neurons and presynaptic terminals. Encoded by the SNCA1/PARK1 gene alpha-synclein is structurally composed of 140 amino acids, making up the three domains: N-terminal membrane binding domain, a hydrophobic non-amyloid-beta component domain and a hydrophilic C-terminal domain. Usually alpha-synuclein plays a role in protecting neurons from apoptotic stimuli and is involved in synaptic vesical trafficking. |
| 存储 | -20°C |
| 参考论文 | Wong and Kranic (2017) α-Synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies. Nat. Med. 23 1 DOI: https://www.nature.com/articles/nm.4269 |
| 分子量 | 1332.7 |
| 多肽序列（单字母） | EGVVHGVTTVAE-[U-13C6,15N2-Lys]-acid |
| 多肽序列（三字母） | Glu-Gly-Val-Val-His-Gly-Val-Thr-Thr-Val-Ala-Glu-[U-13C6,15N2-Lys]-OH |
Alpha-synuclein (46-58) Heavy
Elisa Q.
2020-11-04T19:14:56+08:00
