多肽名称 | [Asn23]-beta-Amyloid (1-40), Iowa Mutation, Human |
纯度 | HPLC ≥ 95% |
描述 | This peptide is naturally occurring mutant within the beta-amyloid region of b-amyloid protein precursor (APP). This mutation is associated with severe cerebral amyloid beta-protein angiopathy (CAA) in Iowa kindred. The affected individuals share a missense mutation in APP at position 694. This site corresponds to residue 23 of beta-amyloid peptide resulting in substitution of asparagine for aspartic acid. |
存储 | -20°C |
参考论文 | Van Nostrand, W. et al. J. Biol. Chem. 276, 32860 (2001); Grabowski, T. et al. Ann. Neurol. 49, 697 (2001). |
分子量 | 4328.9 |
多肽序列(单字母) | DAEFRHDSGYEVHHQKLVFFAENVGSNKGAIIGLMVGGVV |
多肽序列(三字母) | H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asn - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - OH |
[Asn23]-beta-Amyloid (1-40), Iowa Mutation, Human
Elisa Q.
2020-11-04T18:00:42+08:00