多肽名称 | Beta-Amyloid (11-25), Human |
纯度 | HPLC ≥ 95% |
描述 | This amino acids 11 to 22 fragment of b-amyloid is capable of forming well-organized amyloid fibrils in vitro, similar to the pathogenic ones found in amyloidosis. Analysis of the structural properties of one monomer of b-amyloid (11-22) as well as of the aggregation mechanisms for four chains of b-amyloid (11-22) showed that the system assembles rapidly into a random globular state that evolves into three- and four-stranded antiparallel beta-sheets. The aggregation process is considerably accelerated by the presence of preformed dimers. |
存储 | -20°C |
参考论文 | Boucher, G. et al. Proteins 65, 877 (2006); Tjernberg, L. et al. J. Biol. Chem. 274, 12619 (1999). |
分子量 | 1755.0 |
多肽序列(单字母) | EVHHQKLVFFAEDVG |
多肽序列(三字母) | H - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - OH |
Beta-Amyloid (11-25), Human
Elisa Q.
2020-11-04T20:35:39+08:00