多肽名称 | (Pyr¹¹)-Amyloid β-Protein (11-40) |
纯度 | HPLC ≥ 95% |
描述 | pEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV, the N-terminally truncated isoform of the amyloid β-protein (Aβ) beginning with a pyroglutamate (Pyr) residue at position 11 was used in experiments studying the generality of fibrillogenesis-related helix formation. Comparing the fibrillogenesis kinetics of many of the most important clinically relevant amyloid β-protein alloforms it could be observed that among these peptides (Pyr¹¹)-amyloid β-protein (11-40) exhibited the greatest retardation of fibrillization rate. |
存储 | -20°C |
参考论文 | S.S.Mok et al., J. Neurosci. Res., 61, 449 (2000) W.He and C.J.Barrow, Biochemistry, 38, 10871 (1999) C.Russo et al., FEBS Lett., 409, 411 (1997) |
分子量 | 3133.67 |
多肽序列(单字母) | Pyr-VHHQKLVFFAEDVGSNKGAIIGLMVGGVV |
多肽序列(三字母) | Pyr-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH |
(Pyr¹¹)-Amyloid β-Protein (11-40)
Elisa Q.
2020-11-04T17:57:38+08:00