多肽名称 | (Val²)-Amyloid β-Protein (1-42) |
纯度 | HPLC ≥ 95% |
描述 | A mutation very close to the β-secretase cleavage site of APP (A673V). Contrary to the protective Icelandic mutation A2T, the recessive A2V mutation may increase the risk of Alzheimer’s disease. Cantu et al. observed that APP A673V is associated with the early onset of AD-type dementia in homozygous individuals, whereas it has a protective effect in the heterozygous state. |
存储 | -20°C |
参考论文 | M.Rached et al., Biochim. Biophys. Acta, 1689, 229 (2004) |
分子量 | 4542.16 |
多肽序列(单字母) | DVEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
多肽序列(三字母) | H-Asp-Val-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
(Val²)-Amyloid β-Protein (1-42)
Elisa Q.
2020-11-04T18:00:17+08:00