Dalasetron Mesylate Hydrate
Dolasetron Mesylate hydrate (MDL-73147EF hydrate) 是5-HT3受体拮抗剂，用于只治疗化疗引起的恶心和呕吐症状。
中文名：多拉司琼甲磺酸盐一水合物
英文名：Dalasetron Mesylate Hydrate; MDL-73147EF hydrate
CAS 号： 878143-33-0
分子式：C₂₀H₂₆N₂O₇S
分子量：438.49
纯度：>98.0%
| Description | Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
| Target | 5-HT3 Receptor |
| References | [1]. Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8. [2]. Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77. |
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